What is the role of prenatal care in preventing maternal and fetal complications in high-risk pregnancies? Maternal exposure to prenatal stressors is associated with an increased risk of prenatal stress-related complications in high risk pregnancies. Studies have shown that exposure to prenatal stressful stressors is positively associated with maternal depressive symptoms. Moreover, prenatal stressors are associated with increased risk for some types of malformations, including endometrial hyperplasia, and cervical dysplasia. Although maternal exposure to stressors has been shown to be associated with a higher risk of developing certain types of fetal anomalies, recent studies have reported inconsistent findings. This study aimed to investigate the association between prenatal stressors and the risk of developing fetal anomalies in high-resource pregnant women. A total of 58 women with low-resource pregnant live births were recruited from the Obstetric and Gynaecology Unit, University of São Paulo School of Medicine, São Paulo, Brazil. The study included pregnant women with low risk pregnancies (n=31) and high-risk pregnancy (n=38). A total of 50 women with high-risk live births were enrolled and offered the intervention, including prenatal stressors. The main outcome variables included in the analysis were the occurrence of the following neurological, reproductive, and endocrine abnormalities: abnormal thyroid, hypothyroidism, and hyperthyroidism. A significant association was found between prenatal stress and the occurrence of neurological and reproductive abnormalities. These results support the idea that prenatal stressors may be associated with the development of malformation and endocrine dysfunction. Furthermore, these results have important implications for the management of high-risk pregnant women.What is the role of prenatal care in preventing maternal and fetal complications in high-risk pregnancies? (Abstract). The aim of this study was to examine the effect of prenatal care on the risk of maternal and fetal morbidity and mortality in high- and low-risk pregnancies. The study was based on 45,000 women aged 18-74 years; 44,000 women who had had a previous puerperium; and 34,000 women without a history of a previous p reputation. In addition to the data of the study, a similar study was done using the data of a previous pregnancy. After adjusting for the factors of the previous pregnancy, the risk of a maternal and/or fetal complication increased in the highest-risk group (54% versus 19%; P < 0.001). The risk of a fetal complication increased with increasing gestational age (P < 0.05).
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The risk increased with increasing age and duration of the pregnancy (P < or = 0.05), the increase with the duration of the gestation (P
