Botulinum Neurotoxin Therapy

Botulinum Neurotoxin Therapy

Although first used for treatment of eye muscle spasms  .and eye muscle-dysfunction, botulinum neurotoxin canalso be used to reduce facial wrinkles of the forehead and the crow’s-foot· region (i.e., wrinkles emanating from the
lateral canthus)’ around the eyes. Botulinum toxin is produced by the anaerobic microorganism Clostridia botulinum and is responsible for botulism food poisoning, The toxin blocks neurotransmitter release at the neuromuscular  junction and thus temporarily paralyzes the muscle. The temporary paralysis creates long-term muscle weakness and atrophy, The most common region i!ljected for facial rhytids is the forehead and glabellar
region. ,  Very dilute doses can be safel injected with a 30-gauge’needle to selectively paralyze specific facial muscles whose

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