Allogeneic Grafts Medical Assignment Help

Allogeneic Grafts

Also known as allografts or liomogrufts, allogeneic grafh ‘are grafts taken from another individual of the same species. Because- the individuals are usually genetically dissimilar, treating the graft to reduce the antigenicity is
routinely accomplished. Today the most commonly used allogeneic bone is ·freeze-dried. All of these treatments destroy any remaining osteogenic cells in’ the graft, and therefore allogeneic bone grafts cannot participate in
phase I’ osteogenesis. The assistance of these grafts to osteogenesis is purely passive; ‘they offer a hard tissue matrix forphase II induction.
Thus the host must produce all of the esential elements in the graft bed for the allogeneic bone graft to become resorbed and replaced. Obviously, the health of the graft bed is much more important in this set of circumstances
than it is if autogenous bone were to be used. Advantages. Advantages are that allogeneic grafts do , not require another site of operation in the host and that a similar bone or a bone of similar shape to that being, replaced can be obtained (e.g., an allogeneic mandible can be used for  reconstruction of a rnandibulectomy defect). Dlsudvutttagcs. ‘The 0 is advantage is that an allogeneic graft does not provide viable cells for phase I osteogenesis.

Posted by: brianna

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